Health Guide


What is it?

HMB is a supplement used to build muscle. It is also used to treat muscle wasting in acquired immunodeficiency syndrome (AIDS).

Other names for HMB include: Beta-hydroxy-beta-methylbutyrate

Ask your doctor, nurse, or pharmacist if you need more information about this medicine or if any information in this leaflet concerns you.

Before Using:

Tell your doctor if you

  • are taking medicine or are allergic to any medicine (prescription or over-the-counter (OTC) or dietary supplement)
  • are pregnant or plan to become pregnant while using this medicine
  • are breastfeeding
  • have other health problems, such as high blood pressure or heart or blood vessel disease


Talk with your caregiver about how much HMB you should take. The amount depends on the strength of the medicine and the reason you are taking HMB. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle. Do not take more medicine or take it more often than the directions tell you to.

To store this medicine:

Keep all medicine locked up and away from children. Store medicine away from heat and direct light. Do not store your medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down and not work the way it should work. Throw away medicine that is out of date or that you do not need. Never share your medicine with others.


  • Before taking HMB, tell your doctor if you are pregnant or breastfeeding

Side Effects:

Stop taking your medicine right away and talk to your doctor if you have any of the following side effects. Your medicine may be causing these symptoms which may mean you are allergic to it.

  • Breathing problems or tightness in your throat or chest
  • Chest pain
  • Skin hives, rash, or itchy or swollen skin


1. Clark R, Feleke G, Din M et al: Nutritional treatment for acquired immunodeficiency virus-associated wasting using Beta-Hydroxy-Beta-Methylbutyrate, glutamine, and arginine: A randomized, double blind, placebo-controlled study. J Parent Enteral Nutr 2000; 24(3):133-139.

2. Jowko E, Ostaszewski P, Jank M et al: Creatine and Beta-Hydroxy-Beta-Methylbutyrate (HMB) additively increase lean body mass and muscle strength during a weight-training program. Nutrition 2001; 17:558-566.

3. Knitter A, Panton L, Rathmacher A et al: Effects of Beta-Hydroxy-Beta-Methylbutyrate on muscle damage after a prolonged run. J Appl Physiol 2000; 89:1340-1344.

Last Updated: 7/4/2018
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