What is it?
Pregnenolone is a chemical found in the brain that helps make many other chemicals in the body. It is used for sleeping problems, tension and stress, depression, premenstrual syndrome (PMS), to enhance the memory and help stop memory loss in conditions like Parkinson's disease and Alzheimer's.
Other names for Pregnenolone include: Enelone, Natolone, Prenolon, Pregnetan, Pregneton, Arthenolone, and Pregnenolone Sulfate.
Ask your doctor, nurse, or pharmacist if you need more information about this medicine or if any information in this leaflet concerns you.
Tell your doctor if you
- are taking medicine or are allergic to any medicine (prescription or over-the-counter (OTC) or dietary supplement)
- are pregnant or plan to become pregnant while using this medicine
- are breastfeeding
- have other health problems, such as high blood pressure or heart or blood vessel disease
Talk with your caregiver about how much Pregnenolone you should take. The amount depends on the strength of the medicine and the reason you are taking Pregnenolone. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle. Do not take more medicine or take it more often than the directions tell you to.
To store this medicine:
Keep all medicine locked up and away from children. Store medicine away from heat and direct light. Do not store your medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down and not work the way it should work. Throw away medicine that is out of date or that you do not need. Never share your medicine with others.
- Before taking Pregnenolone, tell your doctor if you are pregnant or breastfeeding
- Do not take Pregnenolone if you have or have had prostate cancer (2)
Stop taking your medicine right away and talk to your doctor if you have any of the following side effects. Your medicine may be causing these symptoms which may mean you are allergic to it.
- Breathing problems or tightness in your throat or chest
- Chest pain
- Skin hives, rash, or itchy or swollen skin
Other Side Effects:
This medicine may also cause other side effects. Tell your doctor if you have side effects that you think are caused by this medicine.
1. Smith TS: Renewal of the Anti-Aging Revolution: The Breaktrough Program. Rodale Press, Emmaus, PA; 1998.
2. Grigoryev DN, Long BJ, Njar VC et al: Pregnenolone stimulates LNCaP prostate cancer cell growth via the mutated androgen receptor. J Steroid Biochem Mol Biol 2000; 75(1):1-10.
Last Updated: 4/4/2018