Health Guide


What is it?

DMG is an abbreviation for Dimethyl Glycine. DMG has been used as an antioxidant, anti-aging and anti-cancer agent, and to reduce cholesterol. Most studies, however, have not reported any beneficial effect.

Other names for DMG include: Calcium Pangamate, Pangamic Acid, N,N-Dimethyl Glycine, and Vitamin B15.

Ask your doctor, nurse, or pharmacist if you need more information about this medicine or if any information in this leaflet concerns you.

Before Using:

Tell your doctor if you

  • are taking medicine or are allergic to any medicine (prescription or over-the-counter (OTC) or dietary supplement)
  • are pregnant or plan to become pregnant while using this medicine
  • are breastfeeding
  • have any other health problems, such as high blood pressure or heart or blood vessel disease


Talk with your caregiver about how much DMG you should take. The amount depends on the strength of the medicine and the reason you are taking DMG. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle. Do not take more medicine or take it more often than the directions tell you to.

To store this medicine:

Keep all medicine locked up and away from children. Store medicine away from heat and direct light. Do not store your medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down and not work the way it should work. Throw away medicine that is out of date or that you do not need. Never share your medicine with others.


  • Before taking DMG, tell your doctor if you are pregnant or breastfeeding
  • Some forms of DMG have impurities that have been shown to be mutagenic (cancer causing), especially the ones labeled Pangamic Acid (1,2)

Side Effects:

Stop taking your medicine right away and talk to your doctor if you have any of the following side effects. Your medicine may be causing these symptoms which may mean you are allergic to it.

  • Breathing problems or tightness in your throat or chest
  • Chest pain
  • Skin hives, rash, or itchy or swollen skin

Other Side Effects:

This medicine may also cause other side effects. Tell your doctor if you have side effects that you think are caused by this medicine.


1. Gelernt MD, et al: Mutagenicity of diisopropylamine dichloroacetate, the "active constituent" of vitamin B15 (pangamic acid). Natr Cancer 1982;3(3):129-133.

2. Herbert V, et al: Mutagenicity of dichloroacetate, an ingredient of some formulations of Pangamic acid (trade-named "vitamin B15). Am J Clin Nutr 1980 Jun;33(6):1179-1182.

Last Updated: 7/4/2018
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