Health Guide

Coriolus versicolour

What is it?

Coriolus Versicolour is an herbal medicine used along with other treatments for cancer.

Other names for Coriolus Versicolour include: Cloud Mushroom, PSK, PSP, and Polysaccharide Krestin.

Ask your doctor, nurse, or pharmacist if you need more information about this medicine or if any information in this leaflet concerns you.

Before Using:

Tell your doctor if you

  • are taking medicine or are allergic to any medicine (prescription or over-the-counter (OTC) or dietary supplement)
  • are pregnant or plan to become pregnant while using this medicine
  • are breastfeeding
  • have any other health problems, such as high blood pressure or heart or blood vessel disease


Talk with your caregiver about how much Coriolus Versicolour you should take. The amount depends on the strength of the medicine and the reason you are taking Coriolus Versicolour. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle. Do not take more medicine or take it more often than the directions tell you to.

To store this medicine:

Keep all medicine locked up and away from children. Store medicine away from heat and direct light. Do not store your medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down and not work the way it should work. Throw away medicine that is out of date or that you do not need. Never share your medicine with others.


  • Before taking Coriolus Versicolour, tell your doctor if you are pregnant or breastfeeding
  • Coriolus Versicolour can cause a change in normal liver function (3)

Side Effects:

Stop taking your medicine right away and talk to your doctor if you have any of the following side effects. Your medicine may be causing these symptoms which may mean you are allergic to it.

  • Breathing problems or tightness in your throat or chest
  • Chest pain
  • Skin hives, rash, or itchy or swollen skin

Other Side Effects:

You may have the following side effects, but this medicine may also cause other side effects. Tell your doctor if you have side effects that you think are caused by this medicine.

  • Liver and blood cell functioning can be affected (3)
  • You may have dark colored stools (2)
  • You may experience diarrhea (loose stools) (3)


1. Iino Y, Yokoe T, Maemura M et al: Immunochemotherapies versus chemotherapy as adjuvant treatment after curative resection of operable breast cancer. Anticancer Research 1995;15:2907-2912.

2. Shiu WCT, Leung TWT & Tao M: A clinical study of PSP on peripheral blood counts during chemotherapy. Phytotherapy Research 1992;6:217-218.

3. Mitomi T, Tsuchiya S, Iijima N et al: Randomized controlled study on adjuvant immunochemotherapy with PSK in curatively resected colorectal cancer. Dis Colon Rectum 1992; 35(2): 123-130.

Last Updated: 7/4/2018
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