What is it?
Bromelain is an herbal medicine used to treat swelling, pain, and tenderness caused by inflammation. It is also used to treat menstrual (period) problems, decrease blood clotting, and help in the breakdown of food (digestion).
Other names for Bromelain include: Ananas comosus and Bromelins.
Ask your doctor, nurse, or pharmacist if you need more information about this medicine or if any information in this leaflet concerns you.
Tell your doctor if you
- are taking medicine or are allergic to any medicine (prescription or over-the-counter (OTC) or dietary supplement)
- are pregnant or plan to become pregnant while using this medicine
- are breastfeeding
- have a blood clotting disorder like hemophilia, are on dialysis, or have liver or kidney problems
- have any other health problems, such as high blood pressure or heart or blood vessel disease
Talk with your caregiver about how much Bromelain you should take. The amount depends on the strength of the medicine and the reason you are taking Bromelain. If you are using this medicine without instructions from your caregiver, follow the directions on the medicine bottle. Do not take more medicine or take it more often than the directions tell you to.
To store this medicine:
Keep all medicine locked up and away from children. Store medicine away from heat and direct light. Do not store your medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down and not work the way it should work. Throw away medicine that is out of date or that you do not need. Never share your medicine with others.
Drug and Food Interactions:
Do not take Bromelain without talking to your doctor first if you are taking:
- Blood thinning medicines (examples: warfarin (Coumadin(R)), enoxaparin (Lovenox(R)), dalteparin (Fragmin(R)))
- Before taking Bromelain, tell your doctor if you are pregnant or breastfeeding
- Do not use this medicine if you have hemophilia (easy bleeding or bruising) or any known blood clotting disorder
- Do not use if you are on dialysis for kidney disease
- Do not use if you have severe liver or kidney disease
- Do not use if you have a known allergy to pineapple
Stop taking your medicine right away and talk to your doctor if you have any of the following side effects. Your medicine may be causing these symptoms which may mean you are allergic to it.
- Breathing problems or tightness in your throat or chest
- Chest pain
- Skin hives, rash, or itchy or swollen skin
Other Side Effects:
You may have the following side effects, but this medicine may also cause other side effects. Tell your doctor if you have side effects that you think are caused by this medicine.
- You may experience an increase in heart rate
- Stomach ache, nausea, or diarrhea
- Asthma (difficulty breathing)
- Skin rash with redness and itching
1. Blumenthal M, Busse WR, Goldberg A et al: The Complete Commission E Monographs; Therapeutic Guide to Herbal Medicines. American Botanical Council, Austin, TX; 1998.
2. Brinker F: Herb Contraindications and Drug Interactions. Eclectic Medical Publications, Sandy, OR; 1998.
3. Kleine MW: Introduction to oral enzyme therapy. Int J Immunother 1997; 13:59-65.
4. Kelly GS: Bromelain: A literature review and discussion of its therapeutic applications. Altern Med Rev 1996; 1:243-257.
5. Fachinfo: Traumanase (R)forte, Bromelain. Phone-Poulenc Rorer, A Nattermann & Cie. GmbH, Koeln, Germany; 1997.
6. Zentner A, Jeep S, Wahl R et al: Multiple IgE-medicated sensitizations to enzymes after occupational exposure: evaluation by skin prick test, RAST, and immunoblot. Allergy 1997; 52:928-934.
7. Norred CL & Brinker F: Potential coagulation effects of preoperative complementary and alternative medicines. Alt Ther 2001; 7(6):58-67.
Last Updated: 3/4/2018