HealthSearch

Health Guide

Aminocaproic acid (Intravenous route)

Pronunciation:

a-mee-noe-ka-PROE-ik AS-id

Brand Names:

  • Amicar

Dosage Forms:

  • Solution

Classifications:

Therapeutic—

Hemostatic

Uses of This Medicine:

Aminocaproic acid injection is an antifibrinolytic agent. It is used to treat serious bleeding conditions, especially when the bleeding occurs after dental surgery or other kinds of surgery. This medicine is also sometimes given before an operation to prevent serious bleeding for patients with medical problems that increase the chance of bleeding.

This medicine is available only with your doctor's prescription.

Before Using This Medicine:

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies—

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Children—

Appropriate studies have not been performed on the relationship of age to the effects of aminocaproic acid injection in the pediatric population. Safety and efficacy have not been established.

Older adults—

No information is available on the relationship of age to the effects of aminocaproic acid injection in geriatric patients.

Pregnancy—

Pregnancy CategoryExplanation
All TrimestersCAnimal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast-feeding—

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Other medicines—

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Anti-Inhibitor Coagulant Complex
  • Tretinoin

Other interactions—

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems—

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Blood clots, active or
  • Disseminated intravascular coagulation or DIC (blood clotting problem)—Should not be used in patients with these conditions.
  • Blood clots, history of or
  • Hematuria (blood in the urine)—Use with caution. May make these conditions worse.
  • Kidney disease—The effects of this medicine may be increased because of slower removal of the medicine from the body.

Proper Use of This Medicine:

A nurse or other trained health professional will give you this medicine in a hospital. This medicine is given through a needle placed in one of your veins. The medicine must be injected slowly, so your IV tube will need to stay in place for about 30 to 60 minutes.

Precautions While Using This Medicine:

It is very important that your doctor check your progress while you are using this medicine. Blood tests may be needed to see if the medicine is working properly and to check for unwanted effects.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Side Effects of This Medicine:

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known
Anxiety
black, tarry stools
bleeding gums
bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
blood in the urine or stools
blurred vision
break in the skin, especially associated with blue-black discoloration, swelling, or drainage of fluid
change in the ability to see colors, especially blue or yellow
chest pain or discomfort
chills
confusion
cough or hoarseness
dark-colored urine
decreased frequency or amount of urine
difficult or labored breathing
difficulty with moving
difficulty with speaking
difficulty with swallowing
dizziness or lightheadedness
dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
double vision
fainting
fast heartbeat
fever with or without chills
general feeling of discomfort or illness
general feeling of tiredness or weakness
headache
hives
inability to move arms, legs, or facial muscles inability to speak
increased thirst
itching of the skin
joint pain
loss of appetite
lower back or side pain
muscle aching or cramping
muscle cramps or spasms
muscle pain or stiffness
muscular pain, tenderness, wasting, or weakness
nausea and vomiting
numbness and tingling of the face, fingers, or toes
pain in the arms, legs, or lower back, especially pain in the calves or heels upon exertion
painful or difficult urination
pale, bluish-colored, or cold hands or feet
pinpoint red spots on the skin
problems with bleeding or clotting
puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
shortness of breath
skin rash
slow or irregular heartbeat
slow speech
sore throat
sores, ulcers, or white spots on the lips or in the mouth
sudden shortness of breath or troubled breathing
sweating
swelling
swelling of the face, fingers, or lower legs
swollen glands
swollen joints
tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
tightness in the chest
troubled breathing
unusual bleeding or bruising
unusual tiredness or weakness
vomiting
weak or absent pulses in the legs
weight gain
wheezing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known
Abdominal or stomach pain
confusion as to time, place, or person
continuing ringing or buzzing or other unexplained noise in the ears
decreased vision
diarrhea
ejaculation without semen
hearing loss
holding false beliefs that cannot be changed by fact
mood or mental changes
seeing, hearing, or feeling things that are not there
stuffy nose
unusual excitement, nervousness, or restlessness
watery eyes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.


Last Updated: 7/4/2017
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.

Truven Health Analytics. All rights reserved.

Thomson & A.D.A.M