Health Guide

Digitalis medicine (Oral route, parenteral route)

Brand Names:

  • Digitek
  • Lanoxicaps
  • Lanoxin
  • Lanoxin Pediatric
  • Digitaline Nativelle

Dosage Forms:

  • Tablet
  • Solution
  • Capsule, Liquid Filled
  • Elixir

Uses of This Medicine:

Digitalis medicines are used to improve the strength and efficiency of the heart, or to control the rate and rhythm of the heartbeat. This leads to better blood circulation and reduced swelling of hands and ankles in patients with heart problems.

Although digitalis has been prescribed to help some patients lose weight, it should never be used in this way. When used improperly, digitalis can cause serious problems.

Digitalis medicines are available only with your doctor's prescription.

Before Using This Medicine:


Tell your doctor if you have ever had any unusual or allergic reaction to medicines in this group or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


This medicine has been tested in children and, in effective doses, has not been shown to cause different side effects or problems than it does in adults. However, the dose is very different for babies and children, and it is important to follow your doctor's instructions exactly.

Older adults

Signs and symptoms of overdose may be especially likely to occur in elderly patients, who are usually more sensitive than younger adults to the effects of digitalis medicines.


Digitalis medicines pass from the mother to the fetus. However, studies on effects in pregnancy have not been done in either humans or animals. Make sure your doctor knows if you are pregnant or if you may become pregnant before taking digitalis medicines.


Digoxin passes into breast milk; it is not known if digitoxin passes into breast milk. Although most medicines pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor.

Other medicines

Using medicines in this class with any of the following medicines is not recommended. Your doctor may decide not to treat you with a medication in this class or change some of the other medicines you take.

  • Calcium

Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Alprazolam
  • Amiodarone
  • Azosemide
  • Bemetizide
  • Bendroflumethiazide
  • Benzthiazide
  • Bumetanide
  • Buthiazide
  • Calcium
  • Chan Su
  • Chlorothiazide
  • Chlorthalidone
  • Clarithromycin
  • Clopamide
  • Conivaptan
  • Cyclopenthiazide
  • Cyclothiazide
  • Demeclocycline
  • Diphenoxylate
  • Doxycycline
  • Erythromycin
  • Ethacrynic Acid
  • Furosemide
  • Hydrochlorothiazide
  • Hydroflumethiazide
  • Indapamide
  • Indomethacin
  • Itraconazole
  • Kyushin
  • Lily of the Valley
  • Methyclothiazide
  • Metolazone
  • Midodrine
  • Minocycline
  • Oleander
  • Oxytetracycline
  • Pheasant's Eye
  • Piretanide
  • Polythiazide
  • Propafenone
  • Propantheline
  • Quercetin
  • Quinethazone
  • Quinidine
  • Quinine
  • Ritonavir
  • Saquinavir
  • Spironolactone
  • Squill
  • St John's Wort
  • Succinylcholine
  • Tetracycline
  • Torsemide
  • Trichlormethiazide
  • Verapamil
  • Xipamide

Other interactions

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Other medical problems

The presence of other medical problems may affect the use of medicines in this class. Make sure you tell your doctor if you have any other medical problems, especially:

  • Electrolyte disorders or
  • Heart disease or
  • Lung disease (severe) The heart may be more sensitive to the effects of digitalis medicines.
  • Heart rhythm problems Digitalis medicines may make certain heart rhythm problems worse.
  • Kidney disease or
  • Liver disease Effects may be increased because of slower removal of digitalis medicines from the body.
  • Thyroid disease Patients with low or high thyroid gland activity may be more or less sensitive to the effects of digitalis medicines.

Proper Use of This Medicine:

To keep your heart working properly, take this medicine exactly as directed even though you may feel well. Do not take more of it than your doctor ordered and do not miss any doses. Take the medicine at the same time each day. This medicine works best when there is a constant amount in the blood.

For patients taking the liquid form of digoxin:

  • This medicine is to be taken by mouth even if it comes in a dropper bottle. The amount you should take is to be measured only with the specially marked dropper.

When you are taking digitalis medicines, it is very important that you get the exact amount of medicine that you need. The dose of digitalis medicine will be different for different patients. Your doctor will determine the proper dose of digitalis medicine for you. Follow your doctor's orders or the directions on the label.

After you begin taking digitalis medicines, your doctor may sometimes check your blood level of digitalis medicine to find out if your dose needs to be changed. Do not change your dose of digitalis medicine unless your doctor tells you to do so.

The number of capsules, tablets, drops, or dropperfuls of solution that you take depends on the strength of the medicine.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss a dose of this medicine, and you remember it within 12 hours, take it as soon as you remember. However, if you do not remember until later, do not take the missed dose at all and do not double the next one. Instead, go back to your regular dosing schedule. If you have any questions about this or if you miss doses for 2 or more days in a row, check with your doctor.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Precautions While Using This Medicine:

It is important that your doctor check your progress at regular visits to make sure the medicine is working properly. This will allow your doctor to make any changes in directions for taking it, if necessary.

Do not stop taking this medicine without first checking with your doctor. Stopping suddenly may cause a serious change in heart function.

Keep this medicine out of the reach of children. Digitalis medicines are a major cause of poisoning in children.

Watch for signs and symptoms of overdose while you are taking digitalis medicine. Follow your doctor's directions carefully. The amount of this medicine needed to help most people is very close to the amount that could cause serious problems from overdose. Some early warning signs of overdose are loss of appetite, nausea, vomiting, diarrhea, or problems in seeing. Other signs of overdose are changes in the rate or rhythm of the heartbeat (becoming irregular or slow), palpitations (feeling of pounding in the chest), and/or fainting. In infants and small children, the earliest signs of overdose are changes in the rate and rhythm of the heartbeat. Children may not show the other symptoms as soon as adults.

Your doctor may want you to carry a medical identification card or bracelet stating that you are taking this medicine.

Do not take any other medicine without consulting your doctor. Many over-the-counter (OTC) or nonprescription medicines contain ingredients that interfere with digitalis medicines or that may make your condition worse. These medicines include antacids; laxatives; asthma remedies; cold, cough, or sinus preparations; medicine for diarrhea; and weight reducing or diet medicines.

For patients taking the tablet or capsule form of this medicine:

  • This medicine may look like other tablets or capsules you now take. It is very important that you do not get the medicines mixed up since this may have serious results. Ask your pharmacist for ways to avoid mix-ups with medicines that look alike.

Side Effects of This Medicine:

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

In adults
blurred or yellow vision
feeling of not caring
irregular or slow heartbeat or palpitations (feeling of pounding in the chest)
loss of appetite
lower stomach pain
mental depression
nausea and/or vomiting
seeing or hearing things that are not there
Nosebleeds or bleeding gums
skin rash
With long-term use
Breast enlargement in males
In infants and children

The above signs and symptoms also can occur in infants and children, but heartbeat rate or rhythm side effects are more common initially than stomach upset, loss of appetite, changes in vision, or other side effects.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Last Updated: 6/12/2013
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