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Gabapentin enacarbil (By mouth)

Gabapentin Enacarbil (gab-a-PEN-tin en-a-KAR-bil)

Treats restless leg syndrome (RLS) and pain caused by shingles.

Brand Name(s):

Horizant

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to gabapentin enacarbil.

How to Use This Medicine:

Long Acting Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • It is best to take this medicine with food or milk.
  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: If you miss a dose, skip that dose and go back to your regular dosing schedule.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how gabapentin enacarbil works. Tell your doctor if you are using morphine.
  • Do not drink alcohol while you are using this medicine.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney problems or are receiving dialysis. Tell your doctor if you have a history of depression or mental health problems.
  • This medicine may increase depression or thoughts of suicide. Tell your doctor right away if you start to feel more depressed or think about hurting yourself.
  • This medicine may cause a serious allergic reaction called multiorgan hypersensitivity, which can damage organs and be life-threatening.
  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.
  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.
  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Feeling depressed, agitated, nervous, or irritable, trouble sleeping
  • Fever, rash, swollen or tender glands in the neck, armpit, or groin
  • Unusual changes in mood or behavior, thoughts of hurting yourself

If you notice these less serious side effects, talk with your doctor:

  • Dizziness, drowsiness, sleepiness, tiredness

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 1/27/2017
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