HealthSearch

Health Guide

Alogliptin/metformin (By mouth)

Alogliptin Benzoate (al-oh-GLIP-tin BEN-zoe-ate), Metformin Hydrochloride (met-FOR-min hye-droe-KLOR-ide)

Treats type 2 diabetes.

Brand Name(s):

Kazano

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. Do not use it if you had an allergic reaction to alogliptin or metformin.

How to Use This Medicine:

Tablet

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.
  • It is best to take this medicine with food or milk.
  • Swallow the tablet whole. Do not crush, break, or chew it.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.
  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how this medicine works. Tell your doctor about all other medicines that you are using, especially insulin or other diabetes medicines, acetazolamide, cimetidine, dichlorphenamide, dolutegravir, ranolazine, topiramate, vandetanib, or zonisamide.
  • Limit how much alcohol you drink.

Warnings While Using This Medicine:

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart failure, heart disease, vitamin B12 deficiency, adrenal or pituitary gland disease, or pancreas problems.
  • This medicine may cause the following problems:
    • Lactic acidosis (too much acid in the blood)
    • Pancreatitis
    • Heart failure
    • Liver problems
    • Low blood sugar levels (especially when used with other diabetes medicines)
  • Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may interact with the dye used for an x-ray or a CT scan.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Blistering, peeling, red skin rash
  • Dark urine or pale stools, loss of appetite, stomach pain, yellow skin or eyes
  • Fast breathing, trouble breathing, lightheadedness, severe weakness, tiredness, or confusion
  • Large, hard skin blisters
  • Rapid weight gain, swelling in your hands, ankles, or feet, trouble breathing
  • Severe joint pain
  • Shaking, trembling, sweating, fast or pounding heartbeat, faintness, hunger, confusion
  • Sudden and severe stomach pain, nausea, vomiting, fever

If you notice these less serious side effects, talk with your doctor:

  • Cough, stuffy or runny nose, sore throat
  • Diarrhea

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 12/4/2017
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites.

Truven Health Analytics. All rights reserved.

Thomson & A.D.A.M