Health Guide

Sodium tetradecyl sulfate (By injection)

Sodium Tetradecyl Sulfate (SOE-dee-um tet-ra-DEK-ul SUL-fate)

Treats small varicose veins of the lower legs.

Brand Name(s):


There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

You should not receive this medicine if you have had an allergic reaction to sodium tetradecyl sulfate, or if you have blood clots or cellulitis. You should not receive this medicine if you have an allergic condition or infection, or a blood cell disorder that could weaken your immune system. You should not receive this medicine if you have uncontrolled diabetes, tuberculosis, asthma, cancer, lung disease, skin disease, or overactive thyroid. This medicine is not for treating large varicose veins or varicose veins that are caused by active stomach or pelvic tumors.

How to Use This Medicine:


  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
  • A nurse or other health provider will give you this medicine.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Make sure your doctor knows if you are also using birth control pills.

Warnings While Using This Medicine:

  • Make sure your doctor knows if you are pregnant or breast feeding.
  • Tell your doctor if you have a disorder of your arteries, such as Buerger's disease.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Chest pain, shortness of breath, or coughing up blood.
  • Pain, burning, itching, swelling, or skin changes where the medicine is injected.
  • Pain in your lower leg (calf).

If you notice these less serious side effects, talk with your doctor:

  • Headache.
  • Nausea, vomiting.

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088

Last Updated: 1/4/2018
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