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Triptorelin (By injection)

Triptorelin (trip-toe-REL-in)

Trelstar® treats advanced prostate cancer. Triptodur™ treats premature puberty.

Brand Name(s):

Trelstar

There may be other brand names for this medicine.

When This Medicine Should Not Be Used:

This medicine is not right for everyone. You should not receive it if you had an allergic reaction to triptorelin or similar medicines.

How to Use This Medicine:

Injectable

  • A nurse or other health provider will give you this medicine.
  • Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into one of your muscles.
  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
  • Missed dose: This medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

Drugs and Foods to Avoid:

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products.

  • Some medicines can affect how triptorelin works. Tell your doctor if you are using medicines that can increase prolactin levels in the blood or medicines to treat depression (including bupropion).

Warnings While Using This Medicine:

  • Tell your doctor if you have kidney disease, liver disease, bladder blockage, diabetes, heart or blood vessel disease, heart failure, heart rhythm problems, or a history of seizures, depression, or mental problems.
  • This medicine may cause the following problems:
    • Changes in mood or behavior
    • Increased risk for seizures
    • Heart rhythm problems (including QT prolongation)
    • Changes in blood sugar levels
    • Increased risk of heart attack or stroke
  • Your symptoms may get worse for a few weeks when you begin to use this medicine to treat advanced prostrate cancer. Talk to your doctor if you have concerns.
  • Your child's symptoms might get worse when you first start using this medicine to treat premature puberty, but they should get better as the medicine starts to work. If your child's condition does not begin to improve after using this medicine for 2 months, check with your doctor.
  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Possible Side Effects While Using This Medicine:

Call your doctor right away if you notice any of these side effects:

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
  • Change in how much or how often you urinate, bloody or cloudy urine, difficult or painful urination
  • Depression, mood or behavior changes
  • Fast, slow, pounding, or uneven heartbeat
  • Heavy vaginal bleeding
  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet
  • Seizures
  • Trouble breathing
  • Weakness or loss of muscle control, especially in your legs or feet

If you notice these less serious side effects, talk with your doctor:

  • Bone, back, leg, or joint pain
  • Decreased interest in sex, inability to have or maintain an erection
  • Headache, dizziness
  • Increased hunger or thirst
  • Pain, itching, burning, swelling, or a lump under your skin where the shot was given
  • Warmth or redness in your face, neck, arms, or upper chest

If you notice other side effects that you think are caused by this medicine, tell your doctor

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088


Last Updated: 9/4/2017
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