Pyogenic liver abscess
Pyogenic liver abscess is a pus-filled area in the liver.
Liver abscess; Bacterial liver abscess
There are many possible causes of liver abscesses, including:
- Abdominal infection, such as appendicitis, diverticulitis, or a perforated bowel
- Infection in the blood
- Infection of the bile draining tubes
- Recent endoscopy of the bile draining tubes
- Trauma that damages the liver
A number of common bacteria may cause liver abscesses. In most cases, more than one type of bacteria is found.
Symptoms of liver abscess may include:
- Chest pain (lower right)
- Pain in the right upper abdomen (more common) or throughout the abdomen (less common)
- Clay-colored stools
- Dark urine
- Fever, chills, nightsweats
- Loss of appetite
- Nausea, vomiting
- Unintentional weight loss
- Yellow skin (jaundice)
Exams and Tests
Tests may include:
- Abdominal CT scan
- Abdominal ultrasound
- Blood culture for bacteria
- Complete blood count (CBC)
- Liver biopsy
- Liver function tests
Treatment usually consists of placing a tube through the skin to drain the abscess. Less often, surgery is needed. You will also receive antibiotics for about 4 to 6 weeks. Sometimes, antibiotics alone can cure the infection.
This condition can be life threatening. The risk for death is higher in people who have many liver abscesses.
Life-threatening sepsis can develop.
When to Contact a Medical Professional
Call your health care provider if you have:
- Any symptoms of this disorder
- Severe abdominal pain
- Confusion or decreased consciousness
- High fever that doesn't go away
- Other new symptoms during or after treatment
Prompt treatment of abdominal and other infections may reduce the risk of developing a liver abscess, but most cases are not preventable.
Kim AY, Chung RT. Bacterial, parasitic, and fungal infections of the liver, including liver abscesses. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 84.
Sifri CD, Madoff LC. Infections of the liver and biliary system (liver abscess, cholangitis, cholecystitis). In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, Updated Edition. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 77.
Reviewed By: Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.